[Preprint] Evolution of diapause in the African turquoise killifish by remodeling ancient gene regulatory landscape.
[Review] Fish models for investigating nutritional regulation of embryonic development.
[Preprint] An automated feeding system for the African killifish reveals effects of dietary restriction on lifespan and allows scalable assessment of associative learning.
Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates.
Wang W, Hu CK, Zeng A, Alegre D, Hu D, Gotting K, Ortega Granillo A, Wang Y, Robb S, Schnittker R, Zhang S, Alegre D, Li H, Ross E, Zhang N, Brunet A, Sánchez Alvarado A.
Science. 2020. 369:eaaz3090. doi, PMID, PDF
- Research Highlight: Why some animals have the power of regeneration. Nature. doi
- Research Highlight: Enhancing regeneration. Nat Rev Genet. doi
Vertebrate diapause preserves organisms long term through Polycomb complex members.
- Perspective: A time to grow and a time to pause. Science. 367:851. doi
- News with Video: Watch African killifish embryos enter suspended animation to survive. Science. doi
[Review] The African turquoise killifish: A research organism to study vertebrate aging and diapause.
Comparative phosphoproteomic analysis reveals signaling networks regulating monopolar and bipolar cytokinesis.
[Forum] Non-model model organisms.
Russell JJ, Theriot JA, Sood P, Marshall WF, Landweber LF, Fritz-Laylin L, Polka JK, Oliferenko S, Gerbich T, Gladfelter A, Umen J, Bezanilla M, Lancaster MA, He S, Gibson MC, Goldstein B, Tanaka EM, Hu CK, Brunet A.
BMC Biol. 2017. 15:55. doi, PMID, PDF
The African turquoise killifish genome provides insights into evolution and genetic architecture of lifespan.
Valenzano DR, Benayoun BA, Singh PP, Zhang E, Etter PD, Hu CK, Clément-Ziza M, Willemsen D, Cui R, Harel I, Machado BE, Yee MC, Sharp SC, Bustamante CD, Beyer A, Johnson EA, Brunet A.
Cell. 2015. 163:1539-54. doi, PMID, PDF
Phosphoproteomic analysis of Aurora kinase inhibition in monopolar cytokinesis.
A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.
Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis.
Midbody assembly and its regulation during cytokinesis.
KIF4 regulates midzone length during cytokinesis.
- Cover Article Image
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.
Cell polarization during monopolar cytokinesis.