Publications

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[Preprint] Evolution of diapause in the African turquoise killifish by remodeling ancient gene regulatory landscape.

Singh PA, Reeves GA, Contrepois K, Ellenberger M, Hu CK, Snyder MP, Brunet A.
bioRxiv. 2021. doi, PDF

 


[Review] Fish models for investigating nutritional regulation of embryonic development.

Riddle MR, Hu CK.
Dev Biol. 2021. 476:101-111. doi, PMID, PDF

 


[Preprint] An automated feeding system for the African killifish reveals effects of dietary restriction on lifespan and allows scalable assessment of associative learning.

McKay A, Hu CK, Chen S, Bedbrook CN, Thielvoldt M, Wyss-Coray T, Brunet A.
bioRxiv. 2021. doi, PDF

 


Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates.

Wang W, Hu CK, Zeng A, Alegre D, Hu D, Gotting K, Ortega Granillo A, Wang Y, Robb S, Schnittker R, Zhang S, Alegre D, Li H, Ross E, Zhang N, Brunet A, Sánchez Alvarado A.
Science. 2020. 369:eaaz3090. doi, PMID, PDF

  • Research Highlight: Why some animals have the power of regeneration. Nature. doi
  • Research Highlight: Enhancing regeneration. Nat Rev Genet. doi

 


Vertebrate diapause preserves organisms long term through Polycomb complex members.

Hu CK, Wang W, Brind’Amour J, Singh PP, Reeves GA, Lorincz MC, Alvarado AS, Brunet A.
Science. 2020. 367:870-874. doi, PMID, PDF

  • Perspective: A time to grow and a time to pause. Science. 367:851. doi
  • News with Video: Watch African killifish embryos enter suspended animation to survive. Science. doi

 


[Review] The African turquoise killifish: A research organism to study vertebrate aging and diapause.

Hu CK, Brunet A.
Aging Cell. 2018. 17:e12757. doi, PMID, PDF

 


Comparative phosphoproteomic analysis reveals signaling networks regulating monopolar and bipolar cytokinesis.

Karayel Ö, Şanal E, Giese SH, Üretmen Kagıalı ZC, Polat AN, Hu CK, Renard BY, Tuncbag N, Özlü N.
Sci Rep. 2018. 8:2269. doi, PMID, PDF

 


[Forum] Non-model model organisms.

Russell JJ, Theriot JA, Sood P, Marshall WF, Landweber LF, Fritz-Laylin L, Polka JK, Oliferenko S, Gerbich T, Gladfelter A, Umen J, Bezanilla M, Lancaster MA, He S, Gibson MC, Goldstein B, Tanaka EM, Hu CK, Brunet A.
BMC Biol. 2017. 15:55. doi, PMID, PDF

 


The African turquoise killifish genome provides insights into evolution and genetic architecture of lifespan.

Valenzano DR, Benayoun BA, Singh PP, Zhang E, Etter PD, Hu CK, Clément-Ziza M, Willemsen D, Cui R, Harel I, Machado BE, Yee MC, Sharp SC, Bustamante CD, Beyer A, Johnson EA, Brunet A.
Cell. 2015. 163:1539-54. doi, PMID, PDF

 


Phosphoproteomic analysis of Aurora kinase inhibition in monopolar cytokinesis.

Polat AN, Karayel Ö, Giese SH, Harmanda B, Sanal E, Hu CK, Renard BY, Özlü N.
J Proteome Res. 2015. 14:4087-98. doi, PMID

 


A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.

Harel I, Benayoun BA, Machado B, Singh PP, Hu CK, Pech MF, Valenzano DR, Zhang E, Sharp SC, Artandi SE, Brunet A.
Cell. 2015. 160:1013-1026. doi, PMID, PDF

 


Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis.

Hu CK, Ozlü N, Coughlin M, Steen JJ, Mitchison TJ.
Mol Biol Cell. 2012. 23:2702-11. doi, PMID, PDF

 


Midbody assembly and its regulation during cytokinesis.

Hu CK, Coughlin M, Mitchison TJ.
Mol Biol Cell. 2012. 23:1024-34. doi, PMID, PDF

 


KIF4 regulates midzone length during cytokinesis.

Hu CK, Coughlin M, Field CM, Mitchison TJ.
Curr Biol. 2011. 21:815-24. doi, PMID, PDF

 


Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.

Lin CH, Hu CK, Shih HM.
J Cell Biol. 2010. 189:1097-105. doi, PMID, PDF

  • Cover Article Image
  • Research Highlight: Clathrin teams up to strngthen the spindle. J Cell Biol. doi

 


Cell polarization during monopolar cytokinesis.

Hu CK, Coughlin M, Field CM, Mitchison TJ.
J Cell Biol. 2008. 181:195-202. doi, PMID, PDF

  • Cover Article Image
  • Research Highlight: Polarizing for furrows. J Cell Biol. doi

 


Reassembly of contractile actin cortex in cell blebs.

Charras GT, Hu CK, Coughlin M, Mitchison TJ.
J Cell Biol. 2006. 175:477-90. doi, PMID, PDF

  • Cover Article Image
  • Research Highlight: Cortex consturction. J Cell Biol. doi